Endogenous Enzyme‐Operated Spherical Nucleic Acids for Cell‐Selective Protein Capture and Localization Regulation

Cell-selective regulation of protein translocation is achieved through the rational design an endogenous enzyme-operated spherical nucleic acids platform. The system enables enzyme-activated capture proteins interest and thus their cytoplasmic-nuclear shuttling with tumor-cell specificity, as reported by Mengyuan Li co-workers in Research Article (e202214958).